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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PHACTR4
All Species:
9.09
Human Site:
S344
Identified Species:
22.22
UniProt:
Q8IZ21
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IZ21
NP_001041648.1
702
78211
S344
M
I
S
P
R
S
P
S
P
P
L
P
T
H
I
Chimpanzee
Pan troglodytes
XP_513255
686
76455
S328
M
I
S
P
H
S
P
S
P
P
L
P
T
H
I
Rhesus Macaque
Macaca mulatta
XP_001113123
625
68397
P306
K
P
S
P
P
L
P
P
K
R
G
I
P
S
T
Dog
Lupus familis
XP_544459
729
81127
S375
M
I
P
P
S
S
P
S
P
P
L
P
T
H
I
Cat
Felis silvestris
Mouse
Mus musculus
Q501J7
694
76613
P338
I
P
P
S
S
P
S
P
P
L
P
T
H
I
P
Rat
Rattus norvegicus
P62025
569
62183
T250
A
G
A
E
E
E
A
T
G
K
P
K
A
V
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521719
615
66707
K295
A
P
E
V
P
K
W
K
S
D
L
G
F
G
E
Chicken
Gallus gallus
Q801X6
501
56077
G182
V
M
I
C
M
P
L
G
G
P
D
L
S
S
L
Frog
Xenopus laevis
Q5HZA1
694
76348
A345
K
E
N
A
L
G
P
A
S
L
P
P
T
P
A
Zebra Danio
Brachydanio rerio
Q6PEI3
754
84166
V378
A
Q
G
G
M
N
L
V
P
A
K
P
S
P
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97
82.9
83.2
N.A.
79.3
37.6
N.A.
57.2
34.1
44
39.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
97.2
85
87.5
N.A.
85.3
51.5
N.A.
65.5
47.8
55.8
51
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
20
86.6
N.A.
6.6
0
N.A.
6.6
6.6
20
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
20
86.6
N.A.
13.3
20
N.A.
6.6
33.3
33.3
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
30
0
10
10
0
0
10
10
0
10
0
0
10
0
10
% A
% Cys:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
10
10
0
0
0
0
% D
% Glu:
0
10
10
10
10
10
0
0
0
0
0
0
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% F
% Gly:
0
10
10
10
0
10
0
10
20
0
10
10
0
10
0
% G
% His:
0
0
0
0
10
0
0
0
0
0
0
0
10
30
0
% H
% Ile:
10
30
10
0
0
0
0
0
0
0
0
10
0
10
30
% I
% Lys:
20
0
0
0
0
10
0
10
10
10
10
10
0
0
0
% K
% Leu:
0
0
0
0
10
10
20
0
0
20
40
10
0
0
10
% L
% Met:
30
10
0
0
20
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
10
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
30
20
40
20
20
50
20
50
40
30
50
10
20
20
% P
% Gln:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
10
0
0
0
0
10
0
0
0
0
0
% R
% Ser:
0
0
30
10
20
30
10
30
20
0
0
0
20
20
0
% S
% Thr:
0
0
0
0
0
0
0
10
0
0
0
10
40
0
10
% T
% Val:
10
0
0
10
0
0
0
10
0
0
0
0
0
10
10
% V
% Trp:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _